Technology

Improve outcomes for patients with blood clotting conditions

ClotChip® is a portable, point-of-care device capable of providing both quantitative and qualitative diagnostic evaluation of the patient’s entire hemostatic process. This device leverages miniaturized dielectric spectroscopy to analyze single-drop whole-blood samples to gain patient health insights.

Dielectric spectroscopy is an approach that the Case Western Reserve University electrical engineering team began developing more than eight years ago. The technique applies an external electric field to a drop of blood, and then quantitatively measures the impedance within the biologic fluid. The measurements produced directly correlate to the coagulability or the ability of the blood to clot. This quantitative measurement of coagulability can be translated into a recognizable measured scale.

This method is sensitive to detection of both non-cellular (coagulation factors) and cellular (platelet) abnormalities in hemostatic process and does not require prior knowledge of the patient’s potential condition or application-specific reagents. ClotChip® can even provide valuable data even when the patient’s medical history is unknown.

Technology questions?